Stephen Malina

This is my blog. There are many others like it but this one is mine.


Continuous glucose monitors (CGM) and beyond: A dialogue

What are continuous glucose monitors good for? More broadly, what are continuous measures of physiology (CxM) good for? Similar to Elliot …

What are the bottlenecks to safe, repeatable edits in humans? Part 1

Summary # Gene editing has made a lot of progress over the past few decades. CRISPR-Cas9 sparked the recent fervor and won some of its early …

Dialogue on Viriditas

Introduction # A few months ago, Elliot Hershberg, one of my favorite Substack writers, wrote a post laying out his personal mission. I …

Reflections on 2022

2022 was another exciting, fun year. To round it out, I wrote up some scattered reflections. Enjoy, or if you aren’t a fan of this …

Decentralization of Atoms is Underrated

This post was co-authored with Austin Vernon. Summary # While the internet often focuses its furious debate energy on decentralization in …

GPT4 Predictions

As a way to keep myself honest, I’m going to be recording GPT4 predictions here and archiving versions of the post so I can’t go …

AI Omens: Signs of AI acceleration

A friend recently asked me what my “AI timelines” were. Especially with recent progress in image generation, language modeling, …

Movie Review - Top Gun: Maverick

Since I’ve been going around telling everyone how Top Gun: Maverick (TG:M) is one of the best action movies of our generation, …

Book Review - Elmer Gates and the Art of Mind-using

Introduction # Generally when someone tells you they’ve invented an “art of mind-using” that involves lots of made-up …

2050 Predictions

Introduction # Along with a few internet blogger friends, inspired by Erik Hoel’s post (parts of which I disagree with, including the …


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